Postdoctoral Research Fellow - Gastroenterology Research Center (Finance)
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- 100% paid medical premiums for our full-time employees
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Position Summary:
A postdoc position provides an opportunity for early-career researchers to gain valuable experience, develop independent research skills, and contribute to the advancement of scientific knowledge in their field of expertise.
The post-doctoral fellow will work independently in a multidisciplinary supervised environment on murine and patient derived samples to study pathogenesis of GI diseases including aging pathways and cancer.
The selected candidate has experience working with cell culture and cell treatments as well as with lab-based assays including protein and RNA based techniques. The post doc is expected to be able to draft results of the studies being generated on circadian and microbiota experiments.
Position Key Accountabilities:
1. Interpret and prepare results on omics data (circadian and microbiome related).
2. Develop and maintain organoids from human and mice samples.
3. Develop and maintain immune cells (i.e., macrophages, myofibroblasts, T cells).
4. Conduct in vitro growth of organoids, and immune cells, and perform and optimize co-culture experiments in transwell.
5. Perform DNA extraction, gene expression (qPCR) and protein measurements (western blot, ELISA, and immunofluoresence).
6. Perform co-culture and optimize drug testing on cells and organoids
7. Be familiar with high throughput knock in and knock out cell-based screening.
8. Be familiar with liver image monitoring based on luciferase and fluorescence signals.
9. Work closely with bioinformatics platforms and scientists to generate outputs from circadian and microbiota data.
10. Analyze data and generate figures using scientific computer software (SPSS, R, Prism) and share data with the group for feedback as well as troubleshooting
11. Performs other duties as assigned.
Minimum Education:
Doctoral/Terminal Degree
Knowledge: Molecular biology, in vitro and in vivo experience
Analytical, interpersonal ability to identify needs for projects and ordering appropriate equipment and necessary supplies to conduct studies
Abilities: P roficiency with Microsoft Office, scientific computer software (R, Prism) and basic imaging modalities (Adobe Photoshop, imageJ); Knowledge of handling database
Physical Requirements:
Exerts up to 20 pounds of force occasionally and/or up to 10 pounds frequently and/or a negligible amount constantly to move objects.
Security Sensitive:
This job class may contain positions that are security sensitive and thereby subject to the provisions of Texas Education Code ยง 51.215
Residency Requirement:
Employees must permanently reside and work in the State of Texas.
